产品货号:
Z31212
中文名称:
DHFR抗体
英文名称:
Anti-DHFR Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DHFR Antibody |
指标别名 | DHFR;DHFRP1;dihydrofolate reductase |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF |
基因名称 | DHFR |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human DHFR Key enzyme in folate metabolism.Catalyzes an essential reaction for de novo glycine and purine synthesis,and for DNA precursor synthesis. |
实际分子量 | 21KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Dihydrofolate reductase,or DHFR,is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid,using NADPH as electron donor,which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.In humans,the DHFR enzyme is encoded by the DHFR gene.It is found in the q11→q22 region of chromosome 5.What's more,DHFR belongs to the dihydrofolate reductase family,and it converts dihydrofolate into tetrahydrofolate,a methyl group shuttle required for the de novo synthesis of purines,thymidylic acid,and certain amino acids.DHFR is the key enzyme in folate metabolism.In addition,DHFR catalyzes an essential reaction for de novo glycine and purine synthesis,and for DNA precursor synthesis. |
Uniprot ID | P00374 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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